The Leader in Comprehensive information about YKL-40
MicroVue YKL-40
Product Information
Quidel manufactures a variety of YKL-40 products to support your research. EIA Kits, polyclonal and monoclonal antibodies as well as YKL-40 protien.
More Info
YKL-40 Product Information
Order Information
Click below to get contact information for our products or to see a list of International countries and distributors.
More Info
YKL-40 Order Information
Technical Support
Click below to inquire about product specifications or supporting documents.
More Info
YKL-40 Technical Support

Whats New with YKL-40

May 2011 Come see Quidel SPG at AAI

We will be profiling our research products including assays for bone health and the complement system....
Read Entire Article

Oct 2010 Johansen et al. Clinical Chemistry

Increased plasma YKL-40 is associated with short-term survival in patients with cardiovascular disease and cancer. We tested the hypothesis that increased plasma YKL-40 is associated with total and disease-specific mortality in the general population. ...
Read Entire Article

Apr 2009 Researches identify a role for YKL-40 in tumor angiogenesis

Shao et al presented their findings at the 100th AACR meeting in Denver, Co. The team identified an angiogenic role for YKL-40 in tumor growth and development. Ectopic expression of YKL-40 in MDA-MB-231 breast cancer cells and HCT-116 colon cancer cells led to an extensive angiogenic phenotype of xenografted tumors in SCID/Beige mice and these tumors were 4-8 fold larger than ...
Read Entire Article

Feb 2009 Soel et al J Reproductive Immunology

Preeclampsia is a disease associated with the maternal inflammatory response. YKL-40 and interleukin-18 (IL-18) are inflammatory markers involved in inflammatory states and vascular processes. The aim of this study was to evaluate serum levels of YKL-40 and IL-18 in preeclampsia. Twenty-four patients with preeclampsia and 13 healthy pregnant women were included in this study. S...
Read Entire Article

Feb 2009 Researchers link YKL-40 plasma and tissue expression to ovarian cancer

YKL-40 protein expression was found in cancer cells, tumor associated macrophages, neutrophils and mast cells. The tumor cell expression was higher in OC than in borderline tumors (p = 0.001), and associated with FIGO stage (p < 0.0001) and histological subtype (p = 0.0009). Positive YKL-40 expression (? 5% staining) was not associated with reduced survival. Plasma YKL-40 was a...
Read Entire Article

YKL-40 Research and Development

YKL-40.com is a great resource for comprehensive information about YKL-40, a biomarker with potential application in early diagnosis of cancer. YKL-40 has shown promise in research studies as an early diagnostic and prognostic biomarker in ovarian, colorectal cancer and other cancers as well as rheumatoid arthritis and similar debilitating diseases.
Read More

YKL-40 E-mail Updates

Periodically we send out e-mail updates about YKL-40. If you would like to receive these, please enter your e-mail address on the right.




YKL-40 Background

The biological function of YKL-40 is unknown but it has been shown to be a potent growth factor and a potent migration factor for endothelial cells. While YKL-40 is not significantly expressed in normal tissues, several studies ...

Read More


YKL-40 Publications

There is active research around YKL-40 as a biomarker in a variety of disease states. Recent studies have linked elevated YKL-40 levels to a variety of aggressive and invasive cancers, asthma and cirrhosis.

Read More